Genotypic and phenotypic diversity among Komagataella species reveals a hidden pathway for xylose utilization.

ABSTRACT:

Background

The yeast genus Komagataella currently consists of seven methylotrophic species isolated from tree environments. Well-characterized strains of K. phaffii and K. pastoris are important hosts for biotechnological applications, but the potential of other species from the genus remains largely unexplored. In this study, we characterized 25 natural isolates from all seven described Komagataella species to identify interesting traits and provide a comprehensive overview of the genotypic and phenotypic diversity available within this genus.

Results

Growth tests on different carbon sources and in the presence of stressors at two different temperatures allowed us to identify strains with differences in tolerance to high pH, high temperature, and growth on xylose. As Komaga

SUBMITTER: Heistinger L 

PROVIDER: S-EPMC9036795 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature