Distinctive signatures of pathogenic and antibiotic resistant potentials in the hadal microbiome.

ABSTRACT:

Background

Hadal zone of the deep-sea trenches accommodates microbial life under extreme energy limitations and environmental conditions, such as low temperature, high pressure, and low organic matter down to 11,000 m below sea level. However, microbial pathogenicity, resistance, and adaptation therein remain unknown. Here we used culture-independent metagenomic approaches to explore the virulence and antibiotic resistance in the hadal microbiota of the Mariana Trench.

Results

The results indicate that the 10,898 m Challenger Deep bottom sediment harbored prosperous microbiota with contrasting signatures of virulence factors and antibiotic resistance, compared with the neighboring but shallower 6038 m steep wall site and the more nearshore 5856 m Pacific basin site. Virulenc

SUBMITTER: He L 

PROVIDER: S-EPMC9036809 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature