Fabrication of a novel core-shell-shell temperature-sensitive magnetic composite with excellent performance for papain adsorption.

ABSTRACT: Herein, a novel temperature-sensitive magnetic composite (Fe₃O₄@SiO₂@P(NIPAM-co-VI)/Cu²⁺) with a uniform core-shell-shell structure was successfully prepared via a layer-by-layer method. The resulting magnetic composite revealed good magnetic properties and remarkable affinity to papain with a maximum adsorption capacity of 199.17 mg g^-1. The adsorption equilibrium data fitted the pseudo-second-order kinetic and Freundlich models well, and the major thermodynamics parameters indicated that adsorption was an endothermic and spontaneous process. Fe₃O₄@SiO₂@P(NIPAM-co-VI)/Cu²⁺ could thermally protect papain, which is attributed to the reversible hydrophilic-hydrophobic trans

SUBMITTER: Chen P 

PROVIDER: S-EPMC9036859 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature