Colorimetric and Fluorescence Dual-Mode Biosensors Based on Peroxidase-Like Activity of the Co₃O₄ Nanosheets.

ABSTRACT: The mimic enzyme has become a research hotspot in recent years because of its advantages of high stability, convenient preparation, and low price. In this article, Co₃O₄ nanosheets synthesized by a simple hydrothermal method possess the characteristics of a peroxidase-like activity. The results demonstrated that 3,3',5,5'-Tetramethylbenzidine (TMB) could be oxidized by H₂O₂ to produce a typical blue product (oxTMB) which has a strong absorption at 650 nm wavelength with the help of the Co₃O₄ nanosheets. Thus, a simple and sensitive colorimetric detection method for H₂O₂ was established with a good linear relationship (2-200 μM) and a low limit of detection (0.4 μM). Meanwhile, the colorimetric product c

SUBMITTER: Tan J 

PROVIDER: S-EPMC9037028 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature