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Silica gel-immobilised chiral 1,2-benzenedisulfonimide: a Bronsted acid heterogeneous catalyst for enantioselective multicomponent Passerini reaction.

ABSTRACT: A chiral heterogeneous catalyst derivative of (-)-4,5-dimethyl-3,6-bis(1-naphthyl)-1,2-benzenedisulfonimide is proven here to be efficient in a three-component asymmetric Passerini protocol, carried out in a deep eutectic solvent. Reaction conditions are mild and green, while enantioselectivity is excellent. The catalyst was easily recovered and reused with no decrease in its catalytic activity.

SUBMITTER: Antenucci A

PROVIDER: S-EPMC9037113 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature

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Silica gel-immobilised chiral 1,2-benzenedisulfonimide: a Brønsted acid heterogeneous catalyst for enantioselective multicomponent Passerini reaction.

Antenucci Achille A Marra Francesco F Dughera Stefano S

RSC advances 20210729 42

A chiral heterogeneous catalyst derivative of (-)-4,5-dimethyl-3,6-bis(1-naphthyl)-1,2-benzenedisulfonimide is proven here to be efficient in a three-component asymmetric Passerini protocol, carried out in a deep eutectic solvent. Reaction conditions are mild and green, while enantioselectivity is excellent. The catalyst was easily recovered and reused with no decrease in its catalytic activity. ...[more]

PMID: 35479468

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