Association between sleep parameters and longitudinal shortening of telomere length.

ABSTRACT:

Background

The relationship between sleep parameters and longitudinal shortening of telomere length is unclear. This study aimed to investigate the relationship between sleep parameters and the shortening of leukocyte telomere length (LTL) over a year.

Methods

Among the participants in the validation cohort of the Korea Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease, participants who measured both baseline and follow-up (two years later) of LTL were analyzed. They were dichotomized according to the degree of LTL attrition over two years. Clinical characteristics were compared between the faster and slower LTL shortening groups (cut-off points: -0.710 kbp, n = 119 each). Multivariable logistic regression analyses were performed to deter

SUBMITTER: Jin JH 

PROVIDER: S-EPMC9037260 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature