Prevalence and implications of frailty in acute stroke: systematic review & meta-analysis.

ABSTRACT:

Background

frailty is common in older adults and associated with poor outcomes following illness. Although stroke is predominantly a disease of older people, our knowledge of frailty in stroke is limited. We aimed to collate the literature on acute stroke and frailty to estimate the prevalence of pre-stroke frailty and its associations with outcomes.

Methods

paired researchers searched multidisciplinary electronic databases for papers describing frailty and acute stroke. We assessed risk of bias using Newcastle-Ottawa tools appropriate to study design. We created summary estimates of pre-stroke frailty using random effects models. We collated whether studies reported significant positive associations between frailty and clinical outcomes in adjusted models.

Results

we

SUBMITTER: Burton JK 

PROVIDER: S-EPMC9037368 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature