Electrochemical sensing platform for the simultaneous femtomolar detection of amlodipine and atorvastatin drugs.

ABSTRACT: The development of a proficient and ultra-high sensitive functionalized electrode for accurate analysis of drugs is a long-standing challenge. Herein, we report an electrochemical nanocomposite scaffold, comprising of silver nanoparticles integrated with functionalized carbon nanotubes (COOH-CNTs/Ag/NH₂-CNTs) for the simultaneous quantification of two widely used amlodipine (AM) and atorvastatin (AT) drugs. The sandwiched nanocomposite materials were thoroughly characterized morphologically and structurally. The nanocomposite COOH-CNTs/Ag/NH₂-CNTs immobilized over glassy carbon electrode catalyzed electron transfer reactions at the electrode-electrolyte interface and facilitated detection of targeted drugs, as revealed by the significant decrease in oxidation potentia

SUBMITTER: Kokab T 

PROVIDER: S-EPMC9037620 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature