Improvement of Mineral and Bone Disorders After Renal Transplantation.

ABSTRACT:

Background

Posttransplant mineral and bone diseases are causes of fractures, and their association with cardiovascular events is being studied.

Methods

We analyzed the evolution of biochemical, histological, and imaging parameters pre- and 1 y post-renal transplantation in 69 patients and correlated mineral and bone findings with coronary calcifications. At inclusion and after 12 mo, clinical data and echocardiographic findings were recorded, and laboratory evaluations, radiography of the pelvis and hands, and bone biopsy were performed. Noncontrast cardiac computed tomography was performed during the second evaluation.

Results

Serum levels of fibroblast growth factor 23 and sclerostin decreased in all patients, parathyroid hormone levels decreased in 89.8% of patient

SUBMITTER: Ferreira AC 

PROVIDER: S-EPMC9038238 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature