Menstrual cycle impacts lung structure measures derived from quantitative computed tomography.

ABSTRACT:

Objective

Quantitative computed tomography (qCT) is being increasingly incorporated in research studies and clinical trials aimed at understanding lung disease risk, progression, exacerbations, and intervention response. Menstrual cycle-based changes in lung function are recognized; however, the impact on qCT measures is currently unknown. We hypothesize that the menstrual cycle impacts qCT-derived measures of lung structure in healthy women and that the degree of measurement change may be mitigated in subjects on cyclic hormonal birth control.

Methods

Thirty-one non-smoking, healthy women with regular menstrual cycles (16 of which were on cyclic hormonal birth control) underwent pulmonary function testing and qCT imaging at both menses and early luteal phase time points. Da

SUBMITTER: Sieren JC 

PROVIDER: S-EPMC9038622 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature