Intracranial Large Artery Stenosis and Past Infectious Exposures: Results From the NOMAS Cohort.

ABSTRACT:

Background

Intracranial large artery stenosis (ILAS) is an important contributor to ischemic stroke in the United States and worldwide. There is evidence to suggest that chronic exposure to certain infectious agents may also be associated with ILAS. We aimed to study this association further in an ethnically diverse, prospective, population-based sample of Northern Manhattan.

Methods

We enrolled a random sample of stroke-free participants from an urban, racially, and ethnically diverse community in 1993. Participants have been followed prospectively and a subset underwent brain magnetic resonance angiograms from 2003 to 2008. Intracranial stenoses of the circle of Willis and vertebrobasilar arteries were scored as 0=no stenosis, 1≤50% (or luminal irregularities), 2=50% to 69

SUBMITTER: Mehta A 

PROVIDER: S-EPMC9038664 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature