Impact of prescription isodose level and collimator selection on dose homogeneity and plan quality in robotic radiosurgery.

ABSTRACT:

Purpose

In stereotactic radiosurgery (SRS), prescription isodoses and resulting dose homogeneities vary widely across different platforms and clinical entities. Our goal was to investigate the physical limitations of generating dose distributions with an intended level of homogeneity in robotic SRS.

Methods

Treatment plans for non-isocentric irradiation of 4 spherical phantom targets (volume 0.27-7.70 ml) and 4 clinical targets (volume 0.50-5.70 ml) were calculated using Sequential (phantom) or VOLO^TM (clinical) optimizers (Accuray, Sunnyvale, CA, USA). Dose conformity, volume of 12 Gy isodose (V12Gy) as a measure for dose gradient, and treatment time were recorded for different prescribed isodose levels (PILs) and collimator settings. In addition, isocentric irra

SUBMITTER: Hellerbach A 

PROVIDER: S-EPMC9038902 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature