Ratiometric afterglow luminescent nanoplatform enables reliable quantification and molecular imaging.

ABSTRACT: Afterglow luminescence is an internal luminescence pathway that occurs after photo-excitation, holds great promise for non-background molecular imaging in vivo, but suffer from poor quantitative ability owing to luminescent attenuation over time. Moreover, the inert structure and insufficient reactive sites of current afterglow materials make it hard to design activatable afterglow probes for specific detection. Here, we report a ratiometric afterglow luminescent nanoplatform to customize various activatable afterglow probes for reliable quantification and molecular imaging of specific analytes, such as NO, ONOO^- or pH. Notably, these afterglow probes can not only address the attenuation of afterglow intensity and eliminate the interference of factors (e.g., laser power, irradia

SUBMITTER: Liu Y 

PROVIDER: S-EPMC9039063 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature