Mucinous rectal cancers: clinical features and prognosis in a population-based cohort.

ABSTRACT:

Purpose

Mucinous rectal cancers are generally associated with poor prognosis. This study aimed to clinically characterize mucinous rectal cancers in a defined region of Sweden.

Methods

All patients with rectal cancer in Uppsala and Dalarna, Sweden, between 2010 and 2018, were identified using the Swedish Colorectal Cancer Registry. Data were verified and updated by way of medical, radiology, and histopathology reports. Patients were selected if magnetic resonance imaging, biopsy, and/or surgical specimen were mucinous. Primary outcomes were overall survival (OS), time to recurrence (TTR), pattern of metastatization, and downstaging. Risk factors for recurrence were analysed with univariable and multivariable analyses.

Results

Of 1220 patients with rectal cancer, 263 (

SUBMITTER: Enblad M 

PROVIDER: S-EPMC9039122 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature