Effects of Estradiol on Expression of Estrogen Receptor and Collagen mRNAs in Chick Skin.

ABSTRACT: Skin thickness and strength differ between male and female chickens. This study aimed to clarify the effects of estradiol on the expression of estrogen receptors and collagen mRNA in chicken skin. Estradiol was administered to male chicks for 3 weeks, then cryosections of skin collected from the cervical, thoracic, dorsal, and pelvic limb regions were stained with hematoxylin and eosin, and dermal thickness was measured. Estrogen receptor and collagen mRNA expression was assessed using real-time RT-PCR, and collagen contents were determined. Estradiol did not alter dermal thickness or the collagen content of the skin from any tested region. Among the estrogen receptors, significantly more ESR1 mRNA was expressed in the thoracic skin of chicks administered with estradiol compared wit

SUBMITTER: Nishimura S 

PROVIDER: S-EPMC9039147 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature