Prediction of pregnancy-related hypertensive disorders using metabolomics: a systematic review.

ABSTRACT:

Objective

To determine the accuracy of metabolomics in predicting hypertensive disorders in pregnancy.

Design

Systematic review of observational studies.

Data sources and study eligibility criteria

An electronic literature search was performed in June 2019 and February 2022. Two researchers independently selected studies published between 1998 and 2022 on metabolomic techniques applied to predict the condition; subsequently, they extracted data and performed quality assessment. Discrepancies were dealt with a third reviewer. The primary outcome was pre-eclampsia. Cohort or case-control studies were eligible when maternal samples were taken before diagnosis of the hypertensive disorder.

Study appraisal and synthesis methods

Data on study design, maternal charact

SUBMITTER: Mayrink J 

PROVIDER: S-EPMC9039389 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature