Genomic variation reveals demographic history and biological adaptation of the ancient relictual, lotus (Nelumbo Adans).

ABSTRACT: Lotus (Nelumbo Adans.), a relict plant, is the testimony of long-term sustained ecological success, but the underlying genetic changes related to its survival strategy remains unclear. Here, we assembled the high-quality lotus genome, investigated genome variation of lotus mutation accumulation (MA) lines and reconstructed the demographic history of wild Asian lotus, respectively. We identified and validated 43 base substitutions fixed in MA lines, implying a spontaneous mutation rate of 1.4 × 10-9 base/generation in lotus shoot stem cells. The past history of lotus revealed that the ancestors of lotus in eastern and southern Asia could be traced back ~20 million years ago (Mya) and experienced twice significant bottlenecks and population splits. We further identified the selected genes am

SUBMITTER: Zheng X 

PROVIDER: S-EPMC9039500 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature