The association between common urogenital infections and cervical neoplasia - A nationwide cohort study of over four million women (2002-2018).

ABSTRACT:

Background

Cervical cancer is a major cause of mortality and morbidity in women worldwide. This study aimed to estimate the association between common urogenital infections and cervical neoplasia.

Methods

A multi-register national cohort study of 4,120,557 women aged ≥15 years (2002-2018) was conducted. The outcomes were cervical cancer and carcinoma in situ (Swedish Cancer Register). The main predictors were urogenital infections-(urinary) cystitis, (bacterial) vaginosis, (candida) vulvovaginitis. Incidence rates per 10,000 person-years were calculated (using the European Standard Population). Cox regression was used to estimate hazard ratios (HR) while adjusting for possible confounders-other genital infections (e.g., cervicitis, salpingitis, urogenital herpes), par

SUBMITTER: Jansaker F 

PROVIDER: S-EPMC9039866 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature