Probiotics for the prevention of Hirschsprung-associated enterocolitis.

ABSTRACT:

Background

Hirschsprung-associated enterocolitis (HAEC) is a leading cause of serious morbidity and potential mortality in children with Hirschsprung's disease (HD). People with HAEC suffer from intestinal inflammation, and present with diarrhoea, explosive stools, and abdominal distension. Probiotics are live microorganisms with beneficial health effects, which can optimise gastrointestinal function and gut flora. However, the efficacy and safety of probiotic supplementation in the prevention of HAEC remains unclear.

Objectives

To assess the effects of probiotic supplements used either alone or in combination with pharmacological interventions on the prevention of Hirschsprung-associated enterocolitis.

Search methods

We searched CENTRAL, PubMed, Embase, the China Bio

SUBMITTER: Mei F 

PROVIDER: S-EPMC9039968 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature