Dataset Information

Association of Cardiometabolic Disease With Cancer in the Community.

ABSTRACT:

Background

Obesity and cardiometabolic dysfunction have been associated with cancer risk and severity. Underlying mechanisms remain unclear.

Objectives

The aim of this study was to examine associations of obesity and related cardiometabolic traits with incident cancer.

Methods

FHS (Framingham Heart Study) and PREVEND (Prevention of Renal and Vascular End-Stage Disease) study participants without prevalent cancer were studied, examining associations of obesity, body mass index (BMI), waist circumference, visceral adipose tissue (VAT) and subcutaneous adipose tissue depots, and C-reactive protein (CRP) with future cancer in Cox models.