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Comparison of non-operative versus operative management of resectable colorectal cancer in elderly patients: study protocol for a systematic review.


ABSTRACT:

Background

In the 2021 Statistics Canada census, 18.5% of the Canadian population were senior (65 years and older), among those 1.7 million (4.5%) were aged 80 years and older. Colorectal cancer (CRC) is the third most common cancer in both men and women, with its highest incidence rate in septu- and octogenarians. As clinicians encounter a growing number of very elderly patients (80 years and older) with resectable colorectal cancer, justifying major surgery in a comorbid population with limited life expectancy is difficult. Therefore, this study aims to systemically review the available literature to compare non-operative management to surgical resection with respect to overall survival and quality of life.

Method

We designed and registered a study protocol for a systemati

SUBMITTER: Hu R 

PROVIDER: S-EPMC9040201 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature