Influence of frailty and its interaction with comorbidity on outcomes among total joint replacement.

ABSTRACT:

Background

Patients with frailty get more and more attention in clinical practice. Yet, no large-scale studies have explored the impact of frailty on the perioperative acute medical and surgical complications following TJA. what is more, comorbid diseases may lead, at least additively, to the development of frailty. There also no studies to find the possible interaction between comorbidity and frailty on the postoperative complications after TJA.

Methods

Discharge data of 2,029,843 patients who underwent TJA from 2005 to 2014 from the National Inpatient Sample (NIS) database, which was analyzed using cross-tabulations and multivariate regression modeling. Frailty was defined based on frailty-defining diagnosis clusters from frailty-defining diagnosis indicator of Johns Hopki

SUBMITTER: Lian Q 

PROVIDER: S-EPMC9040243 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature