Interactions between red and processed meat consumption and APOA5 gene variants associated with the incidence of metabolic syndrome in Korean adults.

ABSTRACT:

Background

Metabolic syndrome (MetS) is characterized by the coexistence of disorders such as diabetes, hypertension, hyperlipidemia, and obesity and is affected by genetic factors. Previous genome-wide association studies (GWAS) suggested that APOA5 gene variants were significantly associated with MetS and its components. Dietary factors such as red and processed meat consumption can cause chronic diseases, including hypertension, diabetes, and vascular depression. The aim of this study was to investigate the modulation of the incidence of MetS by the interaction between APOA5 rs662799 polymorphism and red and processed meat consumption.

Methods

In this prospective cohort study, 3266 participants were collected from the Korea Association REsource (KARE) cohort of the Korean

SUBMITTER: Choi WJ 

PROVIDER: S-EPMC9040260 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature