Binding enhancements of antibody functionalized natural and synthetic fibers.

ABSTRACT: Development of low cost biosensing using convenient and environmentally benign materials is important for wide adoption and ultimately improved healthcare and sustainable development. Immobilized antibodies are often incorporated as an essential biorecognition element in point-of-care biosensors but these proteins are costly. We present a strategy of combining convenient and low-cost surface functionalization approaches for increasing the overall binding activity of antibody functionalized natural and synthetic fibers. We demonstrate a simple one-step in situ silica NP growth protocol for increasing the surface area available for functionalization on cotton and polyester fabrics as well as on nanoporous cellulose substrates. Comparing this effect with the widely adopted and low cost

SUBMITTER: Azeem I 

PROVIDER: S-EPMC9041155 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature