Low-cost, open-source 3D printed antibody dispenser for development and small-scale production of lateral flow assay strips.

ABSTRACT: We present a low cost, 3D printed open-source antibody dispenser that can be easily built and used for the development of lateral flow assay (LFA) strips. The fabrication of LFA strips need dispensing of antibodies or antigens in a linear fashion and commercially available dispensers typically cost from few thousands to few tens of thousands of US dollars. In this paper, an antibody dispenser was built by using 3D printed and commercially available parts, which cost no more than 30 USD. This paper presents a detailed instruction on how to assemble the printer and how to achieve a specific line width for the dispensed antibody. By using syringe needles of different gauges, line width ranging from 0.23 to 1.8 mm can be dispensed, and by varying the speed controller, the dispensing needle's s

SUBMITTER: Han W 

PROVIDER: S-EPMC9041196 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature