Uniform wet-Spinning Mechanically Automated (USMA) fiber device.

ABSTRACT: Bioengineering techniques for producing fibers from biomaterials is a growing requirement in medical device technology research and development environments. Scale-up and control of diameter, shape, and length of fibrous proteins and elastomeric polymers are essential to produce defined and consistent materials for experimentation and clinical use. Here, we developed a novel wet spinning fiber extruder and spooler system engineered to draw precipitated fibers several meters in length across five spools. By controlling both the extrusion and spooling rate, the diameter of the fiber can be controlled on the order of 10-1000 µm. Using this system, we extruded and spooled precipitated Type-1 Collagen fibers up to 7.5 m in length on a single spool with a controllable diameter range of 30-50 µm.

SUBMITTER: Mitropoulos AN 

PROVIDER: S-EPMC9041263 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature