A Pragmatic, Randomized Clinical Trial of Gestational Diabetes Screening.

ABSTRACT:

Background

Gestational diabetes mellitus is common and is associated with an increased risk of adverse maternal and perinatal outcomes. Although experts recommend universal screening for gestational diabetes, consensus is lacking about which of two recommended screening approaches should be used.

Methods

We performed a pragmatic, randomized trial comparing one-step screening (i.e., a glucose-tolerance test in which the blood glucose level was obtained after the oral administration of a 75-g glucose load in the fasting state) with two-step screening (a glucose challenge test in which the blood glucose level was obtained after the oral administration of a 50-g glucose load in the nonfasting state, followed, if positive, by an oral glucose-tolerance test with a 100-g glucose lo

SUBMITTER: Hillier TA 

PROVIDER: S-EPMC9041326 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature