Synthesis of cyanooxovanadate and cyanosilylation of ketones.

ABSTRACT: The cyanosilylation was performed by using metavanadate catalysts, and in situ measurements revealed the formation of [VO₂(CN)₃]^2- and [VO₄TMS₂]^- under reaction conditions. The reaction of [VO₂(CN)₃]^2-, trimethylsilyl cyanide (TMSCN), and water afforded [VO₄TMS₂]^- and CN^-, which reacted with ketones to yield the corresponding cyanohydrin trimethylsilyl ethers over [VO₂(CN)₃]^2-. Compound [VO₂(CN)₃]^2- showed high catalytic performance for cyanosilylation of various carbonyl compounds. In the case of n-hexanal, turnover frequency reached up to 250 s^-1.

SUBMITTER: Kikukawa Y 

PROVIDER: S-EPMC9041443 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature