Incidence of anogenital warts after the introduction of the quadrivalent HPV vaccine program in Manitoba, Canada.

ABSTRACT:

Background

The incidence of anogenital warts (AGW) decreased after the introduction of the quadrivalent human papillomavirus (qHPV) vaccine in multiple jurisdictions. We studied how comparing AGW incidence rates with different outcomes affects the interpretation of the qHPV vaccination program. To do this, we replicated multiple study designs within a single jurisdiction (Manitoba).

Methods

We measured the incidence rates of AGW, AGW-related prescriptions, chlamydia, and gonorrhea (the latter two as sham outcomes) between 2001 and 2017 using several clinical and administrative health databases from Manitoba. We then used incidence rate ratios (IRRs) to compare, for each outcome, the rate for the 1997-1998 birth cohort (the first cohorts eligible for the publicly funded qHPV

SUBMITTER: Righolt CH 

PROVIDER: S-EPMC9041799 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature