Rapid and efficient synthesis of formamidines in a catalyst-free and solvent-free system.

ABSTRACT: An operationally rapid and efficient synthesis of N-sulfonyl formamidines that proceeds under mild conditions was achieved by reaction of a mixture of an amine, a sulfonyl azide, and a terminal ynone under catalyst-free and solvent-free conditions. Terminal ynones provide the C source to formamidines via complete cleavage of C[triple bond, length as m-dash]C.

SUBMITTER: Zhou Z 

PROVIDER: S-EPMC9042323 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature