Vertically oriented mesoporous silica film modified fluorine-doped tin oxide electrode for enhanced electrochemiluminescence detection of lidocaine in serum.

ABSTRACT: Owing to a nanochannel-based enrichment effect and anti-fouling ability, highly ordered and vertically oriented mesoporous silica thin film (VMSF) modified electrodes have demonstrated their great potential in direct and highly sensitive analysis of complex samples. In this work, a VMSF modified fluorine-doped tin oxide (FTO) electrode (VMSF/FTO) is fabricated for enhanced electrochemiluminescence (ECL) analysis of lidocaine in serum. VMSF with good integrity and mechanical stability can be rapidly and conveniently grown on FTO in a few seconds at room temperature using an electrochemically assisted self-assembly (EASA) method. Due to the strong electrostatic attraction between the cationic ECL probe and negatively charged nanochannel, the VMSF/FTO electrode shows significant enrichment of

SUBMITTER: Liang R 

PROVIDER: S-EPMC9042675 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature