New facets of nanozyme activity of ceria: lipo- and phospholipoperoxidase-like behaviour of CeO₂ nanoparticles.

ABSTRACT: Cerium dioxide nanoparticles have a special place among engineered nanomaterials due to the wide range of their enzyme-like activities. They possess SOD-, catalase- and peroxidase-like properties, as well as recently discovered phosphatase-, photolyase-, phospholipase- and nuclease-like properties. Advancing biomedical applications of CeO₂-based nanozymes requires an understanding of the features and mechanisms of the redox activity of CeO₂ nanoparticles when entering the vascular bed, especially when interacting with lipid-protein supramolecular complexes (biomembranes and lipoproteins). In this paper, CeO₂ nanoparticles are shown to possess two further types of nanozyme activity, namely lipo- and phospholipoperoxidase-like activities. Compared to a strong

SUBMITTER: Sozarukova MM 

PROVIDER: S-EPMC9043017 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature