Unravelling the Difference Between Men and Women in Post-CABG Survival.

ABSTRACT:

Objectives

Women have a worse prognosis after coronary artery bypass grafting (CABG) surgery compared to men. We sought to quantify to what extent this difference in post-CABG survival could be attributed to sex itself, or whether this was mediated by difference between men and women at the time of intervention. Additionally, we explored to what extent these effects were homogenous across patient subgroups.

Methods

Time to all-cause mortality was available for 102,263 CABG patients, including 20,988 (21%) women, sourced through an individual participant data meta-analysis of five cohort studies. Difference between men and women in survival duration was assessed using Kaplan-Meier estimates, and Cox's proportional hazards model.

Results

During a median follow-up of 5 y

SUBMITTER: Schmidt AF 

PROVIDER: S-EPMC9043514 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature