Ontology highlight
ABSTRACT:
SUBMITTER: Strekalova S
PROVIDER: S-EPMC9043791 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Strekalova Sofia S Kononov Alexander A Rizvanov Ildar I Budnikova Yulia Y
RSC advances 20211122 59
A mild, efficient electrochemical approach to the site-selective direct C-H amidation of benzene and its derivatives with acetonitrile and benzonitrile has been developed. It has been shown that joint electrochemical oxidation of various arenes in the presence of a copper salt as a catalyst and nitriles leads to the formation of <i>N</i>-phenylacetamide from benzene and <i>N</i>-benzylacetamides from benzyl derivatives (up to 78% yield). A favorable feature of the process is mild conditions (roo ...[more]