Imaging of the skin microvascularization using spatially depolarized dynamic speckle.

ABSTRACT:

Significance

We propose a technique devoted to real-time high-resolution imaging of skin microvascularization.

Aim

The process utilizes the temporal variation of the spatially depolarized optical speckle field generated by moving red blood cells when illuminated with fully polarized coherent light.

Approach

Polarimetric filtering prevents the contribution of surface scattering from reaching the camera and thus favors the detection of multiscattered photons from the deeper layers of the skin.

Results

Full-field images reveal the microvasculature with a spatial resolution of 80  μm. The acquisition speed allows for real-time applications.

Conclusions

We demonstrate the ability of this method to determine in 1 s a stable and reliable microvascular activity,

SUBMITTER: Colin E 

PROVIDER: S-EPMC9043838 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature