Characteristics of sleep-disordered breathing in children with down syndrome - A comparison with typically developing children.

ABSTRACT:

Background

Compared with typically developing control children (CC), children with Down syndrome (DS) frequently exhibit sleep-disordered breathing (SDB) and unusual sleep postures (USPs). No studies have directly compared SDB-related signs and symptoms, SDB-related parameters, and USPs between children with DS and CC. This study aimed to evaluate the prevalences of SDB and USPs in children with DS and CC.

Methods

We analyzed SDB-related parameters measured via overnight pulse oximetry and questionnaires administered to parents on SDB-related signs and symptoms, including sleeping postures. Estimated SDB was defined as a 3% oxygen desaturation index (ODI) ≥5 dips/h.

Results

Fifty-one children with DS (4-5 years: N = 12, 6-10 years: N = 23, 11-15 years: N = 16) and six

SUBMITTER: Sawatari H 

PROVIDER: S-EPMC9044005 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature