Graphene oxide-catalyzed trifluoromethylation of alkynes with quinoxalinones and Langlois' reagent.

ABSTRACT: The direct C-H trifluoromethylation of alkynes and quinoxalinones has been achieved using a graphene oxide/Langlois' reagent system. This multi-component tandem reaction using graphene oxide as the catalyst and Langlois' reagent as the robust CF₃ radical source results in the formation of olefinic C-CF₃ to access a series of 3-trifluoroalkylated quinoxalin-2(1H)-ones.

SUBMITTER: Li H 

PROVIDER: S-EPMC9044184 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature