Versatile Macrocyclic Platform for the Complexation of [^natY/⁹⁰Y]Yttrium and Lanthanide Ions.

ABSTRACT: We report a macrocyclic ligand (H₃L⁶) based on a 3,6,10,13-tetraaza-1,8(2,6)-dipyridinacyclotetradecaphane platform containing three acetate pendant arms and a benzyl group attached to the fourth nitrogen atom of the macrocycle. The X-ray structures of the YL⁶ and TbL⁶ complexes reveal nine coordination of the ligand to the metal ions through the six nitrogen atoms of the macrocycle and three oxygen atoms of the carboxylate pendants. A combination of NMR spectroscopic studies (¹H, ¹³C, and ⁸⁹Y) and DFT calculations indicated that the structure of the YL⁶ complex in the solid state is maintained in an aqueous solution. The detailed study of the emis

SUBMITTER: Harriswangler C 

PROVIDER: S-EPMC9044452 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature