Findzx: an automated pipeline for detecting and visualising sex chromosomes using whole-genome sequencing data.

ABSTRACT:

Background

Sex chromosomes have evolved numerous times, as revealed by recent genomic studies. However, large gaps in our knowledge of sex chromosome diversity across the tree of life remain. Filling these gaps, through the study of novel species, is crucial for improved understanding of why and how sex chromosomes evolve. Characterization of sex chromosomes in already well-studied organisms is also important to avoid misinterpretations of population genomic patterns caused by undetected sex chromosome variation.

Results

Here we present findZX, an automated Snakemake-based computational pipeline for detecting and visualizing sex chromosomes through differences in genome coverage and heterozygosity between any number of males and females. A main feature of the pipeline is the

SUBMITTER: Sigeman H 

PROVIDER: S-EPMC9044604 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature