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Facile synthesis of O-acylhydroxamates via reaction of oxime chlorides with carboxylic acids.

ABSTRACT: A simple and efficient method for the synthesis of O-acylhydroxamate derivatives from oxime chlorides and carboxylic acids was developed. The reaction affords clean and facile access to diverse O-acylhydroxamates in high yields (up to 85%). The chemical structure of a typical product was confirmed using single-crystal X-ray structure analysis.

SUBMITTER: Wang KK

PROVIDER: S-EPMC9044751 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature

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Facile synthesis of O-acylhydroxamates via reaction of oxime chlorides with carboxylic acids.

Wang Kai-Kai KK Li Yan-Li YL Zhao Ying-Chao YC Zhang Shan-Shan SS Chen Rongxiang R Sun Aili A

RSC advances 20211220 63

A simple and efficient method for the synthesis of O-acylhydroxamate derivatives from oxime chlorides and carboxylic acids was developed. The reaction affords clean and facile access to diverse O-acylhydroxamates in high yields (up to 85%). The chemical structure of a typical product was confirmed using single-crystal X-ray structure analysis. ...[more]

PMID: 35494140

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