Toxoplasma gondii infection as a risk factor for osteoporosis: a case-control study.

ABSTRACT:

Background

More than one-third of the total world population is infected by Toxoplasma gondii (T. gondii). T. gondii has been linked to various diseases, such as cancer, mental disorders, type 2 diabetes mellitus (T2DM), etc. However, the effects of T. gondii infection on the risk of osteoporosis are unclear. Our study aimed to uncover evidence to determine whether patients exposed to T. gondii have an increased or decreased risk of osteoporosis in people with abnormal bone mineral density (BMD) by using case-control study.

Methods

A total of 729 patients, including 316 osteopenia and 413 osteoporosis patients of Han Chinese ancestry were selected in the study. Their blood samples were collected and the levels of specific IgG antibodies against T. gondii were measured using

SUBMITTER: Zhu K 

PROVIDER: S-EPMC9044867 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature