Evaluation of left atrial function and mechanical dispersion in breast cancer patients after chemotherapy.

ABSTRACT:

Background

Left atrial (LA) function and mechanical dispersion changes in breast cancer patients treated with chemotherapy remain unclear.

Hypothesis

LA function and LA mechanical dispersion in breast cancer patients would be impaired after chemotherapy.

Methods

This single-center retrospective study included 91 consecutive breast cancer patients treated with chemotherapy and 30 controls. Patients were examined by echocardiography three times at intervals. Conventional parameters, left ventricular strain, LA strain, and LA mechanical dispersion were evaluated and compared.

Results

LA strain during reservoir phase (LASr), conduit phase (LAScd), and contraction phase (LASct) all decreased markedly after chemotherapy and were lower than those of the controls (all

SUBMITTER: Chen N 

PROVIDER: S-EPMC9045082 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature