Phylogeographical Landscape of Citrobacter portucalensis Carrying Clinically Relevant Resistomes.

ABSTRACT: During a surveillance study conducted to assess the occurrence and genomic landscape of critical priority pathogens circulating at the human-animal-environment interface in Brazil, as part of the Grand Challenges Explorations-New Approaches to Characterize the Global Burden of Antimicrobial Resistance program, two multidrug-resistant (MDR) Citrobacter portucalensis carrying bla_CTX-M-15 extended-spectrum β-lactamase (ESBL) genes, isolated from green sea turtles, were characterized. Genomic and phylogeographical analysis of C. portucalensis genomes available in public databases revealed the intercontinental dissemination of clades carrying different arrays of clinically relevant genes conferring resistance to carbapenems, broad-spectrum cephalosporins, cephamycins, aminogly

SUBMITTER: Sellera FP 

PROVIDER: S-EPMC9045157 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature