Mining the Flavoproteome of Brucella ovis, the Brucellosis Causing Agent in Ovis aries.

ABSTRACT: Flavoproteins are a diverse class of proteins that are mostly enzymes and contain as cofactors flavin mononucleotide (FMN) and/or flavin adenine dinucleotide (FAD), which enable them to participate in a wide range of physiological reactions. We have compiled 78 potential proteins building the flavoproteome of Brucella ovis (B. ovis), the causative agent of ovine brucellosis. The curated list of flavoproteins here reported is based on (i) the analysis of sequence, structure and function of homologous proteins, and their classification according to their structural domains, clans, and expected enzymatic functions; (ii) the constructed phylogenetic trees of enzyme functional classes using 19 Brucella strains and 26 pathogenic and/or biotechnological relevant alphaproteobacteria together with

SUBMITTER: Minjarez-Saenz M 

PROVIDER: S-EPMC9045290 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature