Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections.

ABSTRACT: To determine neutralizing activity against the severe acute respiratory syndrome coronavirus 2 ancestral strain and 4 variants of concern, we tested serum from 30 persons with breakthrough infection after 2-dose vaccination. Cross-variant neutralizing activity was comparable to that after 3-dose vaccination. Shorter intervals between vaccination and breakthrough infection correlated with lower neutralizing titers.

SUBMITTER: Tober-Lau P 

PROVIDER: S-EPMC9045428 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature