Association between human papillomavirus infection and sudden sensorineural hearing loss: A nationwide population-based cohort study.

ABSTRACT:

Background

While the etiology of sudden sensorineural hearing loss (SSNHL) remains unclear, viral infection has been suggested as a possible cause. Human papillomavirus (HPV) might trigger immune-mediated reaction and induce inflammatory cytokines which are injurious to the cochlea. This study aimed to investigate the association between HPV infection and the risk of developing SSNHL using a nationwide population-based data set.

Methods

In this study, we used the population-based National Health Insurance Research Database of Taiwan to enroll 49,247 individuals with HPV infection from January 1st, 2000, to December 31st, 2013, and compared with a control group of 98,494 individuals who had never been diagnosed with HPV infection (at a 1:2 ratio matched by age, sex, index yea

SUBMITTER: Chen TY 

PROVIDER: S-EPMC9046791 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature