Hearing restoration and the stria vascularis: evidence for the role of the immune system in hearing restoration.

ABSTRACT:

Purpose of review

This article reviews the current literature regarding the pathogenesis of immune-mediated sensorineural hearing loss, utilizes previously published single-nucleus transcriptional profiles to characterize cytokine and cytokine receptor expression in the adult stria vascularis cell types to support immune system interaction with the stria vascularis and reviews the current literature on immunomodulatory agents currently being used for hearing-restoration treatment.

Recent findings

The literature review highlights recent studies that elucidate many cytokines and immune markers, which have been linked to various immune-mediated disease processes that have been observed with sensorineural hearing loss within the stria vascularis and highlights recent publication

SUBMITTER: Samaha NL 

PROVIDER: S-EPMC9047557 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature