Palladium mediated domino reaction: synthesis of isochromenes under aqueous medium.

ABSTRACT: Isochromenes have been synthesized using palladium-catalyzed C-C and C-O bond forming reactions starting from ortho-bromo tertiary benzylic alcohols and internal acetylenes. Notably, this domino process is feasible by using the green solvent, water. The protocol exhibited a broad substrate scope and afforded various isochromenes.

SUBMITTER: Punia L 

PROVIDER: S-EPMC9047682 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature