Prognostic Value of Heterogeneity Index Derived from Baseline ¹⁸F-FDG PET/CT in Mantle Cell Lymphoma.

ABSTRACT:

Objectives

Mantle cell lymphoma (MCL) represents a group of highly heterogeneous tumors, leading to a poor prognosis. Early prognosis prediction may guide the choice of therapeutic regimen. Thus, the purpose of this study was to investigate the potential application value of heterogeneity index (HI) in predicting the prognosis of MCL.

Methods

A total of 83 patients with histologically proven MCL who underwent baseline fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) were retrospectively enrolled. The clinicopathologic index and PET/CT metabolic parameters containing maximum and mean standard uptake value (SUV_max and SUV_mean), metabolic tumor volume (MTV), total lesion glycolysis (TLG), and HI we

SUBMITTER: Liu F 

PROVIDER: S-EPMC9047855 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature