Quantitative MRI Harmonization to Maximize Clinical Impact: The RIN-Neuroimaging Network.

ABSTRACT: Neuroimaging studies often lack reproducibility, one of the cardinal features of the scientific method. Multisite collaboration initiatives increase sample size and limit methodological flexibility, therefore providing the foundation for increased statistical power and generalizable results. However, multisite collaborative initiatives are inherently limited by hardware, software, and pulse and sequence design heterogeneities of both clinical and preclinical MRI scanners and the lack of benchmark for acquisition protocols, data analysis, and data sharing. We present the overarching vision that yielded to the constitution of RIN-Neuroimaging Network, a national consortium dedicated to identifying disease and subject-specific in-vivo neuroimaging biomarkers of diverse neurologi

SUBMITTER: Nigri A 

PROVIDER: S-EPMC9047871 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature